[PHARM-06] Respiratory, Gastrointestinal & Autacoid Pharmacology

PHARM-06 • 2. Pharmacology

Learning Objectives

Apply GINA and Indian Chest Society asthma/COPD stepwise management using ICS+LABA ([4.5] Budesonide, [4.3] Salmeterol, [4.4] Formoterol), SABA ([4.1] Salbutamol), LAMA ([4.8] Tiotropium), and LTRA ([4.9] Montelukast).; Differentiate gastric acid suppression strategies ([5.1] Omeprazole, [5.2] Pantoprazole, [5.7] Famotidine, [5.8] Sucralfate) and H. pylori eradication regimens.; Compare central and peripheral antiemetics ([5.13] Ondansetron, [5.14] Domperidone, [5.15] Metoclopramide) and diarrhoeal management ([5.18] ORS + [5.19] Zinc Sulfate).

Chapter Overview & Core Explanation

Respiratory pharmacology opens constricted airways and calms bronchial inflammation, while gastrointestinal pharmacology regulates stomach acid, gut motility, nausea pathways, and fluid-electrolyte absorption.

Key Exam & Clinical Takeaways

• Patients using inhaled corticosteroids ([4.5] Budesonide, [4.6] Fluticasone) must rinse the mouth and gargle after each actuation to prevent oral candidiasis and hoarseness (dysphonia).
• Proton pump inhibitors ([5.1] Omeprazole, [5.2] Pantoprazole) are prodrugs activated by acid in the parietal cell canaliculus and must be taken 30–60 minutes BEFORE breakfast.

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